Experience:
No experience
Employment Type:
Intern/Co-op
Posted:
4/28/2019
Job Category:
Science
Associate Scientist, Vaccine Process Development
(This job is no longer available)
Merck & Co, Inc. | West Point, PA
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Job Description

Requisition ID: BIO005478

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck's success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world's premier, most research-intensive biopharmaceutical company. Today, we're doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck's leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases.

Applications sought for a scientific opportunity in Merck's Vaccine Bioprocess Research and Development (VBPRD) group.

Individual will serve as an individual scientific contributor responsible for downstream process development of vaccine candidates encompassing multiple modalities including live/attenuated viruses, recombinant protein subunits, and polysaccharide-protein conjugates. The successful candidate is expected to work well in a team atmosphere in close collaboration with cross-functional groups including upstream development, analytical, formulation, and GMP Operations.

The primary job responsibility will be to deliver on specific assigned objectives related to development of robust and scalable processes for the manufacture of clinical supplies and subsequent technical transfer of such processes to GMP operations or manufacturing division. Candidate will, under the close supervision of a more senior scientist, hold responsibility for a range of specific activities including, but not limited to: (1) evaluating downstream process unit operations, (2) chromatography screening and development, (3) membrane filtration, (4) analytical process monitoring, (5) high throughput microscale process development, (6) electronic notebook recording and maintenance, and (7) training for support of GMP operations.

The successful candidate will have a background in bioprocess development and experience in the practice of modern chromatography, membrane, and centrifugation technologies. Experience in programming (e.g. Visual Basic, Python) and statistical & data visualization software (e.g. Excel, Spotfire, JMP, Design Expert) will be considered as a strong positive factors. Individual will have familiarity with biological and biochemical engineering principles and an understanding of the regulatory guidelines governing cGMP manufacture. Key elements of this assignment are (1) to coordinate downstream development activities with upstream process modifications to lock-in a process capable of producing materials for clinical trials, and (2) provide material to support critical assay and formulation development objectives.

Individual is expected to function in a multi-disciplinary environment and to contribute subject matter expertise to various functional teams engaged in development of the vaccine candidate. The successful candidate is expected to demonstrate the ability to communicate results of his/her work in both verbal and written formats. In addition to the core responsibilities outlined above, the candidate is expected to keep careful notes, comply with all required training, and maintain a focused attention on laboratory safety for his or her self and his team.

Qualifications

Education Minimum Requirement:

BS degree (or BS degree to be completed by Spring/Summer of 2019) in Chemical Engineering, Biomedical Engineering, or Biological Sciences preferably with a technical background in downstream (purification) process development of biological molecules

Required Experience and Skills:

* Experience in preparative purification of proteins, viruses, VLPs, and/or other biological molecules.
* Technical background in chromatography, membrane filtration operations, and common biochemical analytical techniques.
* Ability to understand and execute experiments independently in fulfillment of assigned program objectives in a manner that meets quality and time line expectations
* Well-developed organizational, record-keeping, and problem solving skills
* Ability to work independently and/or in a team environment and is results oriented

Preferred Experience and Skills:

* A minimum of 1 years of downstream process development experience for vaccine candidates and/or therapeutic proteins, including experience in process operations scale-up.
* Relevant experience in an academic research laboratory or as intern or co-op in industrial setting may be considered.
* Experience in the purification of live viruses and familiarity with established safety practices for working with such organisms including hands-on experience with Biosafety Level 2 operations
* Experience in programming (e.g. Visual Basic, CC+, MatLab) and statistical/visualization software.
* Communication of scientific information through oral presentations and written documents.
* Conflict management and negotiation skills
* Familiarity with GxP principles and regulations.

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we're counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we're inventing for life.

If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to staffingaadar@merck.com.

Search Firm Representatives Please Read Carefully:

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.

Visa sponsorship is not available for this position.

For more information about personal rights under Equal Employment Opportunity, visit:

EEOC Poster

EEOC GINA Supplement

OFCCP EEO Supplement

Merck is an equal opportunity employer, Minority/Female/Disability/Veteran - proudly embracing diversity in all of it's manifestations.

Job: Bio Process-Purif/Recovery

Other Locations:

Employee Status: Regular

Travel: Yes, 10 % of the Time

Number of Openings: 1

Shift (if applicable):

Hazardous Materials: yes; Chemical

Company Trade Name: Merck

Nearest Major Market: Philadelphia

About Merck & Co, Inc.

Company Description

From developing new therapies that treat and prevent disease to helping people in need, we're committed to improving health and well-being around the world.

We are inspired by the difference we can make in the lives of people around the world through the innovative medicines, vaccines, and consumer health and animal products we discover and produce.

Our products cover a broad range of areas, including heart and respiratory health, infectious diseases, sun care and women’s health. And we focus our research on conditions that affect millions of people around the world – diseases like Alzheimer’s, diabetes and cancer – while building strengths in new areas like biologics.

While we work to develop innovative therapies, we also work hard to make sure they’re affordable. That’s why we offer assistance and discount programs to help make our medicines accessible to those who need them.

At today’s Merck, we’re applying our global reach and strength in scientific research to do more of what we’re passionate about: working to ensure a healthier future for all – one person at a time.

Company History

We've done great things in the past. Today, we're doing great things for the future.

Merck and Schering-Plough recently merged to create a new company. Today, we are the second-largest pharmaceutical company in the world. We also are a global leader in consumer products and animal care.

Both Merck and Schering-Plough have a long and rich history of working to improve people's health and well-being. Through the years, our researchers have helped to find new ways to treat and prevent illness - from the discovery of vitamin B1, to the first measles vaccine, to cold remedies and antacids, to the first statins to treat high cholesterol. Our scientists also have helped develop many products to improve animal health, including vaccines and antibiotics.

While we are proud of our past, we are enthusiastic about the future of this new company and we are excited to help create a healthier, brighter future for people around the world.

Mission & Values

  • Our business is preserving and improving human life. We also work to improve animal health.
  • We are committed to the highest standards of ethics and integrity.
  • We are dedicated to the highest level of scientific excellence and commit our research to improving human and animal health and the quality of life. 
  • We expect profits, but only from work that satisfies customer needs and benefits humanity.
  • Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity and teamwork of our employees.

Working Here

At Merck, you'll find rewarding opportunities, diverse experiences and an unwavering commitment to ethics and integrity. As part of our global team, you'll collaborate with talented and dedicated colleagues whose sense of purpose complements your own. Whatever your career path – whether it's pursuing original science in the laboratory, working directly with our customers, manufacturing quality products or supporting our business in another way – Merck offers opportunities to develop and expand your career while making a true difference in people's lives.  

Hiring Information

No matter what your specialty, there may be a place for you at Merck. We offer opportunities that can make a difference in your career – and in the world. We have career opportunities in various areas:

  • Research & Development
  • Sales & Marketing
  • Manufacturing & Supply
  • Information Services
  • Finance
  • Human Resources
  • Sigma
  • Communications
  • Policy & Philanthropy
  • Legal

Benefits

Our employees are the key to our company's success. We demonstrate our commitment to our employees by offering a competitive and valuable rewards program. Merck's benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and many of the people who matter the most in their lives.

Diversity

Diversity is the power of differences. We believe that having a diverse, inclusive workforce and organization makes us a more innovative and agile company, attuned to the needs of our customers. Every day, we strive to create an inclusive workplace, where diverse perspectives are respected and all opinions matter:

  • Diversity is woven throughout our business practices and training strategy.
  • Our leaders are accountable for specific objectives related to diversity and inclusion. Results are measured in terms of individual, division and company-wide performance.
  • We provide equal employment opportunities to all qualified job applicants.
  • We cast a wide net in our search for talent, seeking qualified suppliers – large and small – from all segments of the business community. This includes minority-, women- and veteran-owned businesses.