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Research Intern
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Jackson Laboratory | Farmington, CT
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Job Description


Research Intern

Verhaak Lab

The Verhaak laboratory at The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a highly motivated individual to work on cell and molecular biology aspects of the projects aimed at understanding the role of extrachromosomal DNA in cancer.

The Verhaak laboratory has recently uncovered an important role for extrachromosomal DNA in cancer (DeCarvalho et al, Nat Genetics, 2018). The successful research intern will play an important role in advancing these studies by performing in-vitro and possibly in-vivo biological experiments to further elevate these findings, with a final goal of leveraging our results for the development of therapeutic modalities that will help improve outcomes for cancer patients. The Verhaak laboratory provides a collegial environment to perform cutting edge cancer research, with a demonstrated track record in helping trainees to successfully apply to graduate or medical school.

The Research Intern position is a temporary position lasting no more than 36 months from the date of beginning of this assignment designed specifically for individuals with a 4 year Life Science, Biology, Computational Biology or applicable degree looking to advance their scientific/research training prior to pursuing further educational endeavors. During the 36 month period, the incumbent is eligible to apply for a permanent position at JAX as long as their performance is rated satisfactory by their Scientific Advisor - but a permanent position is not guaranteed.

The Research Intern works under the direct supervision of a PI or Research Scientist in planning, developing, conducting and evaluating scientific research in a laboratory, clinic, field and/or teaching environment. Incumbents understand the context and implications of the research in order to apply and interpret theoretical knowledge necessary to conduct research in one or more scientific disciplines.

The range of duties includes, but is not limited to: project planning, experimental design, developing methodology, conducting procedures, modifying procedures as needed, data collection and analysis, project management. The incumbent will be expected to regularly develop and deliver presentations at lab meetings, and if appropriate, prepare publications and reports. If deemed appropriate by the PI, individuals will also be able present to the larger laboratory community and external scientific community. It is anticipated that attendance/presentation at external scientific meetings and manuscript preparation will likely occur in yrs 2-3.

If applicable the Research Intern will learn all aspects of proper animal care handling, colony management and biomethods.

Research Interns are able to work flexible shifts to meet the demands of the position that may include evenings, week-ends and/or holidays.

The Research Intern will meet weekly with the PI or Research Scientist mentoring their internship.

The deadline to submit your resume for consideration is May 15, 2019.


* Perform experiments following standard or detailed protocols as per discussions with supervisor/managerPrimary techniques used: Cell culture, Basic and fluorescence microscopy, Transfection, Lentiviral preparation and transduction, DNA/RNA/Protein isolation, PCR/qPCR, Western blot, Immunocytochemistry/histochemistry, FISH (Flourescence in-situ hybridization), Mini/midi/maxi plasmid preps, DNA subcloning, CRISPR-Cas9-based genetic engineering experiments.
* Analysis of obtained data using standard statistical methods and interpretation of findings.
* Preparation of research reports, literature reviews, scientific papers, and/or assistance with drafting and generating preliminary data for research proposals in consultation with the Principal Investigator; develops and delivers presentations at lab meetings as well as to the larger Laboratory community and external scientific community.


* Bachelor's degree in life sciences, biological sciences or related discipline - Previous experience in an academic setting performing cell and molecular biology experiments; interpreting and evaluating results, and compiling data preferred. - Explicit interest in pursuing and completing eligibility requirements for continuing studies in biomedical and/or clinical research; or in pursuing a medical profession.- The ability to work in a demanding, fast paced, team-oriented environment, while maintaining a high-level of professionalism- Leads and initiates good safety practices and a demonstrated history of safe conduct- Exceptional technical skills, good understanding of principles of biological experiments and of projects under study- Ability to interact in a productive, professional and positive manner to enhance the outcome of the goals of the research program - Demonstrated team player with professional, positive attitude and willingness to be flexible- Consistently maintains a positive work environment - Demonstrated ability to positively influence the behavior of teammates - Ability to work flexible shifts (evening/week-end/holiday) - Regular, reliable and consistent attendance

About Us

The Jackson Laboratory (JAX, www.jax.org) is a nonprofit biomedical research institute with over 2,000 employees whose mission is to discover precise genomic solutions for human disease and empower the global biomedical community in the shared quest to improve human health. A National Cancer Institute-designated Cancer Center, JAX has a mammalian genetics headquarters in Bar Harbor, Maine, a facility in Sacramento, California, and a genomic medicine facility, The Jackson Laboratory for Genomic Medicine (JAX-GM), in Farmington, Connecticut.

The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.

JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients' lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 "Best Places to Work in Academia" in the United States in a poll conducted by The Scientist magazine!

Our Values:

INTEGRITY - Courage and commitment to do what is right

PEOPLE - Inspiring our people to enhance the health of all

ONE TEAM - Unified by our promise to transform medicine and science

EXCELLENCE - Achieving world-class results

INNOVATION - Leading with discovery and creative solutions

STEWARDSHIP - Caring for and enhancing the resources entrusted to us

What do we have to offer?

JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program, an onsite full service cafeteria, and a fully operational primary care facility available to employees and their families.

Most importantly, every position contributes to JAX's mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Learn more about career opportunities at JAX: http://www.jax.org/careers.

About Jackson Laboratory

The Jackson Laboratory was founded in 1929 as a cancer research facility, and has been designated as a Cancer Center by the National Cancer Institute since 1983 to conduct basic research. The continuing mission of The Jackson Laboratory is to discover the genetic basis for preventing, treating and curing human disease, and to enable research and education for the global biomedical community. Based in Bar Harbor, Maine, The Jackson Laboratory has a large presence in Maine and is the state's sixth largest non-profit organization.