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Bioinformatics Scientist 1
Illumina, Inc. | San Diego, California
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Job Description

Bioinformatics Scientist

Our team specializes in developing algorithms and software for genomic data, from raw data through interpreted human genomes.  Challenges in this area include handling specific sample types or variant calling problems.  In addition, assembling methods into an end-to-end pipeline poses integration challenges.  We develop methods to address these challenges and provide a sample-to-answer pipeline with high reliability, speed, and completeness of results.

We are seeking an exceptional individual to join our team in developing DNA analysis solutions for use by researchers and clinicians worldwide.  These methods will be key to of population-scale sequencing projects, sample-to-actionable-answer analysis for rare and undiagnosed genetic disease and for oncology.


  • Creation and iterative enhancement of sequence analysis workflows (i.e. read alignment, variant calling, and variant annotation) to support both research and clinical products.
  • Design, prototype, and implement computational algorithms that utilize both statistical and machine learning approaches.
  • Software optimization at the design, algorithm, and source code level.
  • Collaborate deeply with other teams to ensure a smooth, end-to-end workflow with external organizations.


  • Strong background in developing production-grade software. Experience with C#, C++ is highly advantageous.
  • Personal initiative and ability to work effectively as part of a team.
  • Familiarity with applying statistical approaches to algorithm development.
  • Superior written and verbal communication skills.

Illumina believes that everyone has the ability to make an impact, and we are proud to be an equal opportunity employer committed to providing employment opportunity regardless of sex, race, creed, color, gender, religion, marital status, domestic partner status, age, national origin or ancestry, physical or mental disability, medical condition, sexual orientation, pregnancy, military or veteran status, citizenship status, and genetic information. If you have a disability or special need that requires accommodation, please contact us at applications@illumina.com. To learn more, visit: https://www.dol.gov/ofccp/regs/compliance/posters/pdf/eeopost.pdf

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