Experience:
1-3 years of experience
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Employment Type:
Full time
Posted:
8/25/2017
Job Category:
Research
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Scientist I, ES / iPSC Assay & Screening Technologies
Biogen | Cambridge, Massachusetts
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Job Description

External Posting TitleScientist I, ES / iPSC Assay & Screening Technologies
Job DescriptionBiogen is seeking a highly motivated molecular and cellular biologist to join the Discovery Bioassays team within Biotherapeutic & Medicinal Sciences. Our group develops assays, executes high throughput screens (HTS) and pursues the subsequent assessment of active small molecules as part of a collaborative team of biologists and chemists. The primary responsibilities for this position include development and implementation of innovative cell-based assays using high throughput technologies to support hit identification and lead optimization of small molecules. It is preferred that the candidate have experience with neurobiology, small format cell culture and automated liquid handling. The successful candidate will accomplish our mission through open communication, innovation, teamwork, creative problem solving, and use of state-of-the-art technologies.

Duties & Responsibilities:


• Strong background on cell-based assay development and familiarity with automation.

• Deep understanding of neurological cell models including ES/iPSC differentiation, handling of primary cells and routine cell lines.

• The candidate is expected to design scientific experiments and perform comprehensive data analysis using specialized software to process HTS and dose response data (e.g. TIBCO Spotfire, Genedata Screener).

• Demonstrated broad expertise in various assay methodologies including high content analysis (confocal microscopy), MSD, and protein-protein interaction readouts (e.g. FRET/BRET, AlphaLISA).

• Maintain ELN entries and data reporting to support medicinal chemistry efforts.



*LI-SRC6
LocationCambridge, MA, US
Job CategoryResearch
Requisition Number32285BR
Qualifications
• Previous experience developing/troubleshooting assays and running HTS campaigns is required.

• The successful candidate will be highly motivated with a demonstrated ability to successfully take on challenges and quickly adapt to new responsibilities.

• Excellent oral and written communication skills are necessary.
Education
• This position requires a Ph.D. with 0-4 years of experience. Will also consider equivalent experience.
About BiogenCorporate Overview

Through cutting-edge science and medicine, Biogen discovers, develops and delivers worldwide innovative therapies for people living with serious neurological and neurodegenerative diseases. Biogen is a pioneer in biotechnology and today the Company has the leading portfolio of medicines to treat multiple sclerosis (MS), has introduced the first and only approved treatment for spinal muscular atrophy, and is at the forefront of neurology research for conditions including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis (ALS). Biogen also manufactures and commercializes biosimilars of advanced biologics. Our global organization of nearly 7,000 employees is committed to a single mission: making a meaningful difference in the lives of patients with few or no treatment options.

One of the pioneers in biotechnology, Biogen was founded in 1978 and today serves patients in nearly 90 countries. Our global headquarters and R&D operations are located in Cambridge, Massachusetts, with an international headquarters in Zug, Switzerland, world-class manufacturing facilities in Research Triangle Park, North Carolina, USA and Hillerod, Denmark, and affiliate locations around the world.

Our Science

We aspire to have the greatest impact on patients and science of any biotechnology company in the history of our industry. To us, that means creating novel medicines that benefit individuals and society, and bringing new scientific understanding to diseases for which there are no adequate treatments.

For nearly two decades Biogen has led in the research and development of new therapies to treat MS, including the most prescribed oral treatment in the world. Now our research is driving revolutionary new MS treatments with the goal of reversing or even repairing damage caused by the disease. We are now applying our neurological expertise to solve some of most challenging and complex diseases of the brain, including Alzheimer's disease, Parkinson's disease, and ALS. As we uncover new insights into human biology, Biogen is employing cutting-edge technologies to discover potential treatments for rare and genetic disorders.

Biogen is revolutionizing biologics manufacturing, developing the industry's most advanced plants and processes. This expertise is used to produce both original innovative therapies and biosimilars that expand patient access to lower-cost medicines.

Our Corporate Citizenship

The same intellectual discipline and passion that drives our science is reflected in our corporate citizenship, environmental sustainability, and commitment to diversity and inclusion. As a company, we are focused on improving science education and limiting the impact of our company on the environment. In 2015, we became a carbon neutral company and ranked first place on Newsweek's 2015 Green Rankings, and we are an industry leader on the Dow Jones Sustainability World Index. Biogen was named to Science's list of Top Employers of 2015 and in 2017 received a perfect score of 100 for the fourth consecutive year on the Human Rights Campaign (HRC) Corporate Equality Index, which also named Biogen as one of its Best Places to Work.

All qualified applicants will receive consideration for employment without regard to sex, gender identity or expression, sexual orientation, marital status, race, color, national origin, ancestry, ethnicity, religion, age, veteran status, disability, genetic information or any other basis protected by federal, state or local law. Biogen is an E-Verify Employer in the United States.

Please be advised that all legitimate correspondence from a Biogen employee will come from "@biogen.com" email accounts.

About Biogen

Biogen Idec Inc. is engaged in the development, manufacturing, and commercialization of therapies. The Company's products address diseases such as multiple sclerosis, lymphoma and rheumatoid arthritis. The Company has four products: AVONEX (interferon beta-1a), RITUXAN (rituximab), TYSABRI (natalizumab) and FUMADERM (dimethylfumarate and monoethylfumarate salts). AVONEX is used in the treatment of relapsing forms of multiple sclerosis (MS). RITUXAN is used in the treatment of relapsed or refractory low-grade or follicular, CD20-positive, and B-cell, non-Hodgkin's lymphomas (B-cell NHLs). TYSABRI is approved for the treatment of relapsing forms of MS. FUMADERM acts as an immunomudulator. It also has product candidates, such as BG-12 (acquired with the purchase of Fumapharm), ANTI-CD80 antibody/(galiximab), ANTI-CD23 antibody/(lumiliximab), Ocrelizumab/(Humanized ANTI-CD20 Antibody) and Lixivaptan.In January 2007, the Company completed the acquisition of Syntonix Pharmaceuticals, Inc. (Source: 10-K)

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