No experience
Employment Type:
Full time
Job Category:
Bioinformatics Programmer I
(This job is no longer available)
Grad Date

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Job Description

The HGSC was founded in 1996 under the leadership of Dr. Richard Gibbs and is a world leader in genomics. The fundamental interests of the HGSC are in advancing biology and genetics by improved genome technologies. As one of the three large-scale sequencing centers funded by the National Institutes of Health, the HGSC provides a unique opportunity to work on the cutting-edge of genomic science in a state of the art institution. Today, the HGSC employs ~ 200 staff, and it occupies more than 36,000 square feet on the 14th, 15th, and 16th floors of the Margaret M. and Albert B. Alkek Building. The HGSC is located on the southwest edge of downtown Houston, the fourth largest city in the U.S., in the Texas Medical Center, the world's largest medical complex. The major activity of the HGSC is high- throughput DNA sequence generation and the accompanying analysis. The HGSC is also involved in developing the next generation of DNA sequencing and bioinformatics technologies that will allow greater scientific advances in the future. This entry-level position with the Next-Generation Sequencing Informatics (NGSI) group requires a bioinformatics programmer with Unix command line experience. This opportunity in a fast-paced academic environment will enable a qualified candidate to rapidly gain NGS experience.

At the HGSC Bioinformatics Core, NGSI manages the production, maintenance and primary analysis of all HGSC genome sequence data, including HiSeq X Ten, and Novaseq informatics. NGSI also contributes to multiple clinical, Mendelian, and large cohort sequencing studies, specifically in the areas of structural variation and at-scale genomic data science. Under the direction of a senior manager, a qualified candidate will assist with running the research informatics pipelines, troubleshooting routine production issues, and tracking project data.

* Support routine NGSI production efforts
* Work with NGSI Production team to innovate


* Bachelor's degree in Computer Science or Biological Sciences.
* No experience required.


* Knowledge of Perl, HTML, CGI, C++, relation databases and SQL.
* Programming in a UNIX/LINUX environment.
* Familiarity with XML,BASH,Python
* Common NGS data formats (FASTQ,BAM,VCF)
* Next-Gen Sequencing tools (SAMtools,BWA,etc)

About Baylor College of Medicine

Baylor College of Medicine, one of the nation's top academic health sciences centers, is committed to advancing human health through the integration of patient care, research, education and community service. The only private medical school in the Greater Southwest, Baylor College of Medicine was founded in 1900 and is today an internationally respected medical and research institution known for excellence in education, research and patient care. The College consistently ranks among the top of the country's 125 medical schools. For 2007, U.S. News & World Report has ranked the College No. 10 on its list of top medical schools. Baylor College of Medicine also is listed 13th among all U.S. medical schools for National Institutes of Health funding, and No. 1 for research expenditures in biological science by the National Science Foundation.